子宫内膜异位症治疗新进展

目的探讨研究治疗子宫内膜的新进展，观察腹腔镜手术联合孕三烯酮治疗子宫内膜异位症的治疗效果和远期影响。方法随机选取于2010年1月-2013年3月在该院诊治的子宫内膜异位症的患者120例，其中经腹腔镜完成手术，并术后给予孕三烯酮治疗的患者60例为观察组；60例经腹腔镜手术未进行药物治疗的为对照组。观察组在术后第1次月经后开始进行孕三烯酮的服用，2次／周，连续服用6个月，并进行随访观察，记录。结果两组患者都采用了腹腔镜手术，过程类似，术后处理如尿管拔出、注射抗生素、住院时间基本一致。术后疗效：观察组的患者经过治疗后病情完全缓解的患者达到52例，占总人数的86．7％，术后复发患者6例，占总例数的10％，其中正常排卵的患者50例，占总例数的83．33％，生育需求患者妊娠的为16例，占总例数的75％。，而对照组的患者病情完全缓解的患者达到39例，占总例数的65％，术后复发患者19例，占总例数的31．6％，其中正常排卵的患者48例，占总例数的80％，生育需求患者妊娠的为10例，占总例数的55％。观察组的各项指标均优于对照组，差异有统计学意义（P〈0．05）。结论腹腔镜手术治疗子宫内膜异位症安全有效、患者恢复快已成为现今医生与患者的最佳选择，孕三烯酮也是近年来用于治疗子宫内膜异位症的一种有效药物，腹腔镜手术联合孕三烯酮联合治疗子宫内膜异位症不仅能促进治疗效果的提升，还能有效预防复发，有着十分积极的影响，值得临床推广应用。

The New Progress in the Treatment of Endometriosis

Objective To explore the research progress in the treatment of endometriosis, observe the efficacy and long-term effect of laparoscopic surgery combined with gestrinone on endometriosis. Methods 120 cases of patients with endometriosis diagnosed and treated in our hospital from January, 2010 to March, 2013 were randomly selected and divided into two groups, 60 cases in the observation group were treated with laparoscopic surgery and given gestrinone postoperatively, and the other 60 cases in the control group were given laparoscopic surgery without medication. The observation group took gestrinone after the first menstruation postoperatively, twice a week, for 6 months, and they were followed up, the conditions of them were recorded. Results Both groups underwent laparoscopic surgery, the processes were similar, postoperative treatment such as pulling out the catheter, injection of antibiotics, length of hospital stay were basically consistent. Postoperative efficacy： after the treatment, of the observation group, there were 52 cases of patients with complete remission, accounting for 86.7%, 6 patients with postoperative recurrence, accounting for 10%, including 50 patients with normal ovulation, accounting for 83.33%, 16 cases of patients demanding for birth were pregnant, accounting for 75%; and of the control group, there were 39 cases of patients with complete remission, accounting for 65%, 19 patients with postoperative recurrence, accounting for 31.6%, including 48 patients with normal ovulation, accounting for 80%, 10 cases of patients demanding for birth were pregnant, accounting for 55%. The indicators of the observation group were better than those of the control group, and the differences between the two groups were statistically significant （P〈0.05）. Conclusion Laparoscopic surgery is safe and effective in the treatment of patients with endometriosis with rapid recovery, which has become the best choice for doctors and patients at present. And gestrinone is an effective drug used in the treatment of endometriosis in recent years. Laparoscopic surgery combined with gestrinone in the treatment of endometriosis can not only improve the therapeutic effect, but also effectively prevent the recurrence, which has a very positive effect, and is worthy of clinical popularization and application.