| 重组人脑利钠肽联合环磷腺苷葡胺治疗急性心力衰竭的近期疗效 |
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| 引用本文： | 王玲玲.重组人脑利钠肽联合环磷腺苷葡胺治疗急性心力衰竭的近期疗效[J].中外医疗,2014,0(9):21+23-21,23. |
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| 作者姓名： | 王玲玲 |
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| 作者单位： | 王玲玲(桂林市妇女儿童医院 红十字会博爱医院妇幼保健院 心血管内科,广西桂林,541001)； |
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| 摘 要： | 目的探讨重组人脑利钠肽联合环磷腺苷葡胺治疗急性心力衰竭的近期疗效。方法将62例急性心力衰竭患者随机分为对照组和观察组，均给予环磷腺苷葡胺治疗，仅观察组加用重组人脑利钠肽；分析治疗前后的呼吸症状改善情况，左室心功能和血浆生化指标水平及不良反应。结果观察组的好转率高于对照组（80．65％VS．54．84％，P〈0．05），左室心功能和血浆生化指标均优于对照组（P〈0．05）。结论重组人脑利钠肽联合环磷腺苷葡胺治疗急性心力衰竭的近期疗效较好，可耐受。
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| 关 键 词： | 脑钠肽 环磷腺苷葡胺 急性心力衰竭 近期疗效 |
The Short-term Effect of Recombinant Human Brain Natriuretic Peptide and Me~lumine Adenosine Cyclophosphate on Acute Heart Failure |
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| WANG Lingling.The Short-term Effect of Recombinant Human Brain Natriuretic Peptide and Me~lumine Adenosine Cyclophosphate on Acute Heart Failure[J].China Foreign Medical Treatment,2014,0(9):21+23-21,23. |
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| Authors: | WANG Lingling |
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| Institution: | WANG Lingling( Cardiovascular Department, Guilin Women＇ s and Children＇ s Hospital (Boai Hospital of Guiling Red Cross Society/Guilin Maternal and Child Health Hospital), Guilin, Guangxi Zhuang Autonomous Region, 541001, China) |
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| Abstract: | Objective To explore the short-term effect of recombinant human brain natriuretic peptide （rhBNP） and meglumine adenosine cyclophosphate on acute heart failure. Methods 62 patients with acute heart failure were randomly divided into the control group and the observation group. Both groups were treated with meglumine adenosine cyelophosphate. In addition, the observation group was given rhBNP. The improvement of respiratory symptoms, left ventrieular function, plasma biochemical parameters and the adverse reactions of two groups before and after treatment were analyzed. Results The improvement rate of the observation group was higher than that of the control group （80.65% vs. 54.84%, P〈0.05）; the left ventricular function and plasma biochemical indicators were superior to those of the control group （P〈0.05）. Conclusion The short-term effect of recombinant human brain natriuretic peptide and meglumine adenosine cyclophosphate on acute heart failure was better and which was tolerable. |
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| Keywords: | Brain natriuretic peptide Meglumine adenosine cyclophosphate Acute heart failure Short-term effect |
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