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高胆固醇血症患者循环血小板衍化生长因子的变化
引用本文:胡子旺.高胆固醇血症患者循环血小板衍化生长因子的变化[J].心肺血管病杂志,1994,13(2):102-103.
作者姓名:胡子旺
作者单位:衡阳医学院第一附属医院心血管内科
摘    要:采用生物活性法测定血循环中血小板衍化生长因子(PDGF)活性。结果表明高胆固醇血症患者循环PDGF活性明显增高。提示高胆固醇血症患者PDGF的改变可能与内皮细胞损害及原癌基因异常表达有关,高活性的PDGF又与动脉粥样硬化平滑肌细胞增殖有密切的关系。

关 键 词:高胆固醇血症,血小板衍化生长因子

Change of Circulatory Platelet-Derived Growth Factor in Hypercholesterolemia
Hu ziwang.Change of Circulatory Platelet-Derived Growth Factor in Hypercholesterolemia[J].Journal of Cardiovascular and Pulmonary Diseases,1994,13(2):102-103.
Authors:Hu ziwang
Abstract:Activity of platelet derived growth factor(PDGF) in blood was determined. The results indicated that activity of PDGF increased significantly in hypercholesterolemia. It might be related with endothelial lesions and overexpression of oncogenes. Meanwhile, high activity of PDGF was also related with proliferation of smooth muscle cells in atherosclerosis.
Keywords:Hypercholesterolemia  Platelet derived  growth factor
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