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| 祛痰化瘀解毒方药对高脂血症痰瘀互阻证患者单核细胞亚群异常的影响 | |
| 引用本文： | 曾辉,徐丽丽,王亚红,王宪波,宋剑南,尚涛,马雅銮,郝禹,韩俊燕,韩俊阁,陈冰. 祛痰化瘀解毒方药对高脂血症痰瘀互阻证患者单核细胞亚群异常的影响[J]. 中国中西医结合杂志, 2011, 31(1): 23-27 |
| 作者姓名： | 曾辉 徐丽丽 王亚红 王宪波 宋剑南 尚涛 马雅銮 郝禹 韩俊燕 韩俊阁 陈冰 |
| 作者单位： | 1. 中国中医科学院中医基础理论研究所,北京,100700 2. 北京中医药大学附属东直门医院,北京,100700 3. 首都医科大学传染病研究所,北京,100069 |
| 基金项目： | 北京市自然科学基金资助项目(No.7102119); 中国中医科学院自主选题研究项目(No.ZZ-20006008) |
| 摘 要： | 目的 研究高脂血症痰瘀互阻证患者外周血单核细胞亚群比例及其表面受体TLR4、CD163和CD36表达变化，初步探讨和评价祛痰化瘀解毒方药干预的治疗效果。 |
| 关 键 词： | 高脂血症；痰瘀互阻证；单核细胞亚群；祛痰化瘀解毒方药 |
Impact of Qutan Huayu Jiedu Herbs on Monocyte Subpopulations Abnormality in Patients with Hyperlipidemia of Phlegm-Stagnancy Obstruction Syndrome Pattern |
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| WANG Ya-hong,MA Ya-luan,HAN Jun-yan. Impact of Qutan Huayu Jiedu Herbs on Monocyte Subpopulations Abnormality in Patients with Hyperlipidemia of Phlegm-Stagnancy Obstruction Syndrome Pattern[J]. Chinese journal of integrated traditional and Western medicine, 2011, 31(1): 23-27 | |
| Authors: | WANG Ya-hong MA Ya-luan HAN Jun-yan |
| Affiliation: | MA Ya-luan,WANG Ya-hong,HAN Jun-yan,et al The Institute of Basic Theory,China Academy of Chinese Medical Sciences,Beijing (100700) |
| Abstract: | Objective To investigate the distribution of monocyte subpopulations and the changes of Toll-like receptor 4 (TLR4),CD163 and CD36 expressions in the peripheral blood of patients with hyperlipidemia of phlegm-stagnancy obstruction syndrome pattern (HLE-PSO),and to evaluate the intervening effects of Qutan Huayu Jiedu (QHJ) herbs on these parameters. Methods Monocytes in the peripheral blood were sorted using flow cytometry into 3 subpopulations:the CD14high CD16-(Mo1),the CD14high CD16+ (Mo2a) and the CD14l... |
| Keywords: | hyperlipidemia phlegm-stagnancy obstruction syndrome monocyte subpopulations Qutan Huayu Jiedu Herbs |
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