小剂量右美托咪定复合丙泊酚用于高血压患者全身麻醉下纤维支气管镜的观察

目的 观察输注小剂量右美托咪定对原发性高血压患者喉罩辅助通气丙泊酚复合瑞芬太尼全身麻醉下纤维支气管镜检查的麻醉效果.方法 选择患有原发性高血压需择期行纤维支气管镜检查患者40例,其中男、女各20例,随机分为两组（n=20）.麻醉诱导前后分别记录观察组（DEX组）和对照组（生理盐水组）术前（T0）、麻醉诱导前（T1）、麻醉诱导后（T2）、气管镜入声门后1 min（T3）、3 min（T4）、5 min（T5）、术后唤醒即刻 （T6）,各时点的SBP、DBP、ECG、HR、SpO2数据.结果 两组均患者顺利完成检查.与对照组比较,观察组检查期间呛咳少,丙泊酚等麻醉及辅助用药量少,血流动力学更趋平稳.结论 诱导前 15 min 微量泵输注0.4 μg/kg右美托咪定可以安全用于原发性高血压患者纤维支气管镜麻醉.

Observation of small doses of dexmedetomidine and propofol as general anesthesia for hypertensive patients under fiberoptic bronchoscopy

Objective To observe the effect of general anesthesia by low doses of dexmedetomidine and propofol on patients with essential hypertension under fiberoptic bronchoscope. Methods 40 patients with hypertension, who needed to be checked with broncho- scope, were randomly divided in two groups （n = 20）. The data of SBP, DBP, ECG, HR and SpO~ were recorded in the observation group （DEX group） and the control group （normal saline group） respectively at the timing points including pre-operation （To ）, pre-in- duced anesthesia （TI ）, post-induced anesthesia （T2 ）, bronchoscope through glottis 1 min later （T3 ）, bronchoscope through glottis 3min later （ T4 ）, brom.hc,~.ope through glottis 5rain later （ T3 ）, and recovery time immediately after operation （ T6 ）. Results The patients in the two groups wete all successfully completed this check. Compared with the control group, patients in the observation group had less cough, less adjunctive medicine, and more balance of hemodynamics. Conclusion Micropump infusion of 0.4 μg/kg of dexmedetomi- dine 15 minutes before inducement can be safely applied on patients with essential hypertension for bronchoscope anesthesia.