米仔兰枝条中杀虫活性成分研究

目的 研究中国传统民族植物药米仔兰(又称树兰)Aglaia odorata Lour．枝条中杀虫活性成分。方法 以生物测定为指导，采用硅胶柱、Sephadex LH-20柱以及制备薄层分离板对其成分进行分离和纯化，并通过物化性质和光谱分析对其结构鉴定。结果从中分离得到7个化合物，分别鉴定为rocaglamide(Ⅰ)、desmethyl rocaglamide(Ⅱ)、8-methoxymarikarin(Ⅲ)、7-羟基-6-甲氧基-香豆素(Ⅳ)、3′-hydroxy—methylrocaglate(Ⅴ)、3′-hydroxy—rocaglamide(Ⅵ)、marikarin(Ⅶ)。结论 化合物Ⅳ为首次从Aglaia Lour．属植物中分离得到，化合物Ⅲ和Ⅶ为首次从米仔兰植物中分离得到。

Insecticidal active constituents from twig of Aglaia odorata

Object To study the insecticidal activity constituents from the twigs of traditional Chinese folk medicine "Mizilan" or "Shu-Lan" (Aglaia odorata Lour. ). Methods Seperation and purification under bioassay-directed were performed on silica gel CC, Sephadex LH-20 CC and preparative TLC. Their structures were established on the basis of physicochemical and spectral analysis. Results Seven compounds were isolated and identified as rocaglamide ( Ⅰ ), desmethyl rocaglamide ( Ⅱ ), 8-methoxymarikarin (Ⅲ), 7-hydroxy-6-methoxy-coumarin (Ⅳ), 3′-hydroxy-methylrocaglate (Ⅴ), 3′-hydroxyrocaglamide (Ⅵ), marikarin (Ⅶ), respectively. Conclusion Compound Ⅳ is isolated from the plant of Aglaia Lour. for the first time and compounds Ⅲ and Ⅶ are isolated from A. odorata for the first time.