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Evolutionary changes in the genome of Mycobacterium tuberculosis and the human genome from 9000 years BP until modern times
Affiliation:1. Centre for Clinical Microbiology, Division of Infection & Immunity, University College London, London, UK;2. Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;3. Kuvin Center for the Study of Infectious & Tropical Diseases and Ancient DNA, Hadassah Medical School, The Hebrew University, Jerusalem, Israel;4. Centre for the History of Medicine, Division of Biosciences, University College London, London, UK;5. Al-Quds Nutrition and Health Research Institute, Faculty of Medicine, Al-Quds University, Abu-Deis, P.O. Box 201760, West Bank, Palestine;6. Department of Anthropology, Hungarian Natural History Museum, Budapest, Hungary;7. Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel;8. Paleo-DNA Laboratory, Departments of Anthropology and Biology, Lakehead University, Thunder Bay, Ontario, Canada;1. Natural History Museum Vienna, Department of Anthropology, Burgring 7, A-1010 Wien, Austria;2. University of Natural Resources and Life Sciences Vienna, Department of Chemistry, Division of Analytical Chemistry, VIRIS Laboratory, Konrad-Lorenz-Straße 24, A-3430 Tulln, Austria;3. Natural History Museum Vienna, Central Research Laboratories, Burgring 7, A-1010 Wien, Austria;4. VERA (Vienna Environmental Research Accelerator) Laboratory, University of Vienna, Währingerstrasse 17, A-1090 Wien, Austria;1. Department of Biological Anthropology, University of Szeged, Szeged, Hungary;2. Laboratoire d''anthropologie biologique Paul Broca, École Pratique des Hautes Études, UMR 5199 PACEA, Université de Bordeaux, Pessac, France;3. Department of Anthropology, University of Western Ontario, Canada;4. Unité de Recherche MIVEGEC – UR 224/IRD – UMR 5290/CNRS – UM1 – Université Montpellier 2, Montpellier, France;5. Institut de Biologie Intégrative de la Cellule (I2BC), CEA-CNRS-UPS, UMR9198, Bât 400, F-91400 Orsay, France;6. Institute for Mummies and the Iceman, EURAC Research, Bolzano, Italy;1. Laboratory of Molecular Biology Applied to Mycobacteria, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil;2. Laboratory of Biology of Recognition, Universidade Estadual do Norte Fluminense, Rio de Janeiro, Brazil;3. Laboratory of Bacterial Pathogenesis and Molecular Biology, Unicamp, São Paulo, Brazil;4. Instituto Adolfo Lutz, São Paulo, Brazil;5. Laboratorio de Micobacteriologia Molecular do Centro de Pesquisas em Doenças Infecciosas e Parasitarias, University Hospital Clementino Fraga Filho, UFRJ, Rio de Janeiro, Brazil;6. Laboratory of Molecular Microbiology, St. Petersburg Pasteur Institute, St. Petersburg, Russia;7. Laboratory of Microbiology, Research Institute of Phthisiopulmonology, St. Petersburg, Russia;1. Department of Biological Anthropology, University of Szeged, Szeged, Hungary;2. Centre for Clinical Microbiology and Centre for the History of Medicine, University College London, London, UK;3. Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK;4. Organic Geochemistry Unit, School of Chemistry, University of Bristol, Bristol, UK;5. National Mass Spectrometry Service Centre, School of Medicine, Grove Building, Swansea University, Swansea, UK;1. Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK;2. Biodiversity Institute and Departments of Anthropology and Geology, University of Kansas, Lawrence, KS 66045, USA;3. Kuvin Center for the Study of Infectious and Tropical Diseases and Ancient DNA, Hadassah Medical School, Hebrew University, Jerusalem, Israel;4. Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel;5. Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Rehovot, Israel;6. Centres for Clinical Microbiology and the History of Medicine, University College London, UK
Abstract:
Keywords:Ancient DNA  Evolution  KIR historical specimens  Solute Carrier family genes
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