Cost-Effectiveness of a Nonpharmacological Intervention in Pediatric Burn Care |
| |
| Affiliation: | 1. Centre for Children’s Burns and Trauma Research, Queensland Children’s Medical Research Institute, The University of Queensland, Royal Children’s Hospital, Brisbane, Australia;2. Queensland Children’s Medical Research Institute, The University of Queensland, Royal Children’s Hospital, Brisbane, Australia;3. School of Population Health, The University of Queensland, Brisbane, Australia;4. Tissue Repair and Regeneration Program, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia;5. Division of Occupational Therapy, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia;6. Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA |
| |
| Abstract: | ObjectiveTo report the cost-effectiveness of a tailored handheld computerized procedural preparation and distraction intervention (Ditto) used during pediatric burn wound care in comparison to standard practice.MethodsAn economic evaluation was performed alongside a randomized controlled trial of 75 children aged 4 to 13 years who presented with a burn to the Royal Children’s Hospital, Brisbane, Australia. Participants were randomized to either the Ditto intervention (n = 35) or standard practice (n = 40) to measure the effect of the intervention on days taken for burns to re-epithelialize. Direct medical, direct nonmedical, and indirect cost data during burn re-epithelialization were extracted from the randomized controlled trial data and combined with scar management cost data obtained retrospectively from medical charts. Nonparametric bootstrapping was used to estimate statistical uncertainty in cost and effect differences and cost-effectiveness ratios.ResultsOn average, the Ditto intervention reduced the time to re-epithelialize by 3 days at AU$194 less cost for each patient compared with standard practice. The incremental cost-effectiveness plane showed that 78% of the simulated results were within the more effective and less costly quadrant and 22% were in the more effective and more costly quadrant, suggesting a 78% probability that the Ditto intervention dominates standard practice (i.e., cost-saving). At a willingness-to-pay threshold of AU$120, there is a 95% probability that the Ditto intervention is cost-effective (or cost-saving) against standard care.ConclusionsThis economic evaluation showed the Ditto intervention to be highly cost-effective against standard practice at a minimal cost for the significant benefits gained, supporting the implementation of the Ditto intervention during burn wound care. |
| |
| Keywords: | burns child cost-effectiveness economic evaluation nonpharmacological intervention randomized controlled trial re-epithelialization |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
