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Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA
Affiliation:1. Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada;2. Molecular Model Discovery Laboratory, Department of Chemistry and Biotechnology, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Melbourne, Victoria 3122, Australia;3. Department of Medical Microbiology and Immunology, Katz Centre for Health Research, University of Alberta, Edmonton, Alberta, Canada;4. Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Alberta, Canada;5. Li Ka Shing Applied Virology Institute, University of Alberta, Edmonton, Alberta, Canada;1. Department of Toxicology, University of Würzburg, Würzburg, Germany;2. Institute of Pathology, University of Würzburg, Würzburg, Germany;3. Bayer Pharma AG, Wuppertal, Germany;4. Merck Serono, Non-Clinical Safety, Darmstadt, Germany;1. Laboratory for the Analysis of Medicines, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège, Liège, Belgium;2. Laboratory of Pharmacognosy, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège, Liège, Belgium;1. Mucosal Immunity Research Group, State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China;2. Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany;3. Institute for Virology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany;1. Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University Medical Center, Stanford, CA, USA;2. Arrowhead Research Corporation, Pasadena, CA, USA;3. The University of Hong Kong, Hong Kong, China;4. Victorian Infectious Diseases Reference Laboratory, Victoria, Australia;5. Hong Kong Polytechnic University, Hong Kong, China
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