Impact de la modulation d’intensité dans l’irradiation des aires ganglionnaires du cancer du sein |
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| Institution: | 1. Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX;2. Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX;3. Department of Radiation Oncology, The University of Texas Medical Branch at Galveston, Galveston, TX;1. Département de radiothérapie oncologique, centre Antoine-Lacassagne, université de Nice Sophia Antipolis, 33, avenue de Valombrose, 06189 Nice cedex 2, France;2. Unité de biostatistiques, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex 2, France;3. Service d’urologie et de transplantation, hôpital Archet 2, centre hospitalier universitaire de Nice, université de Nice Sophia Antipolis, 151, route de Saint-Antoine, 06202 Nice cedex 3, France;4. Département de radiologie, hôpital Pasteur, centre hospitalier universitaire de Nice, 30, voie Romaine, 06001 Nice cedex 1, France;5. Laboratoire central d’anatomie pathologique, hôpital Pasteur, centre hospitalier universitaire de Nice, 30, voie Romaine, 06001 Nice cedex 1, France;1. Department of Radiation Oncology, Georges François Leclerc Cancer Center, 21000 Dijon, France;2. Department of Biostatistics, Georges François Leclerc Cancer Center, 21000 Dijon, France;3. Department of Radiation Oncology, Division of Medical Physics, Georges François Leclerc Cancer Center, 21000 Dijon, France;4. Department of Radiation Oncology, Division of Medical Physics, Institut Curie, 75000 Paris, France;1. Department of Radiation Oncology and Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya, 68, Pesochny-2, 194291 St. Petersburg, Russia;2. Department of Surgery No. 1 (Breast Cancer), N.N. Petrov Institute Oncology, Leningradskaya, 68, Pesochny-2, 194291 St. Petersburg, Russia |
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| Abstract: | Irradiation of node areas is still a complex challenge in external radiotherapy for breast cancer. Acceptable target coverage is always balanced by protection of organs at risk and patient morphology. Intensity-modulated radiotherapy increases the quality of dose distribution on the planning target volume, but modifies dramatically the irradiation coverage of critical structures in a different way compared to 3D treatment. In this paper we analyze this new technique in breast treatment with node regions, its expected gain and potential risks. |
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| Keywords: | IMRT Lymph node areas Breast cancer |
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