| 慢性阻塞性肺疾病及慢性肺心病血清红细胞生成素的研究 |
| |
| 引用本文： | 叶燕青,李伯埙,程时荫.慢性阻塞性肺疾病及慢性肺心病血清红细胞生成素的研究[J].武汉大学学报(医学版),1997(3). |
| |
| 作者姓名： | 叶燕青 李伯埙 程时荫 |
| |
| 作者单位： | Department of Respiratory Disease，Second Affiliated Hospital，Hubei Medical University，Wuhan 430071，China |
| |
| 摘 要： | 为了探讨慢性阻塞性肺疾病患者缺氧状态下红细胞生成素（Ｅｒｙｔｈｒｏｐｏｉｅｔｉｎ，ＥＰ）是否增加，其变化规律如何，用５＿Ｈ３＿ＵＲ掺入体外生物法测定了２３例慢性支气管炎肺气肿，２９例慢性肺原性心脏病及２５例正常人血清ＥＰ水平，同步测定动脉血气及血红蛋白（ＨＢ）、红细胞计数（ＲＢＣ）等，结果发现伴明显低氧血症的患者血清红细胞生成素水平升高，说明缺氧使红细胞生成素增加。红细胞生成素与ＰａＯ２有一定规律的联系，红细胞生成素增高者并非都伴有继发性红细胞增多。
|
| 关 键 词： | 肺疾病.阻塞性／血液 肺心病／血液 红细胞生成素 |
Serum Erythropoietin in Chronic Obstructive Pulmonary Disease and Cor Pulmonale |
| |
| Abstract: | erum erythropoietin (EP), arterial blood gas and red blood cells (RBC) and hemoglobin (HB) were tested in 23 patients with chronic obstructive pulmonary disease (COPD, group A),29 patients with chronic cor pulmonale (group B) and 25 normal subjects (group C),and EP was measured with 5_H3_UR bioassay in vitro. In group B, EP was significantly higher than that of group A or group C (P<0.01).Hypoxemia was present in group B.Elevated EP was associated with hypoxemia but did not nesessarily lead to polycythemia. |
| |
| Keywords: | lung diseases obstructive/BL pulmonary heart disease/BL erythropoietin |
| 本文献已被 CNKI 等数据库收录！ |
