HLA Antigens and Steroid Responsive Nephrotic Syndrome of Childhood |
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| Authors: | D. O'Regan U. O'Callaghan S. Dundon D. J. Reen |
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| Affiliation: | Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin, Dublin 12, Ireland |
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| Abstract: | Fifty-four unrelated children with steroid responsive nephrotic syndrome of childhood were studied for 24 alleles at the HLA–A and B loci. A significantly increased incidence of HLA–B8 ( P c < 0.01) was observed compared to controls.
No association between response to cyclophosphamide therapy and HLA antigens was seen. |
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