急性脑梗死患者抑郁与病灶部位的相关性研究

目的探讨脑梗死患者抑郁与病灶部位的关系。方法对78例脑梗死患者利用汉密顿抑郁量表(HAMD)进行检查后,将患者分为抑郁组和非抑郁对照组,选用磁共振成像(MRI)进行病灶部位和范围的检测,评定患者的抑郁与病灶部位的相关性。结果脑梗死患者抑郁的发生率为42.3%;2组患者大脑半球左侧和右侧比较,差异无统计学意义(P>0.05);前部和后部、皮层和皮层下比较,差异有统计学意义(P<0.05);大脑前、中动脉供血区比较,差异无统计学意义(P>0.05);大脑前、中动脉供血区与大脑后动脉供血区比较,差异有统计学意义(P<0.05)。结论脑梗死患者的抑郁与病灶部位有相关性,大脑半球前部、皮层损伤及大脑半球大脑前、中动脉供血区损伤,更可能导致抑郁。

Study of related factors between location of cerebral infarction and depression

Objective To evaluate the related factors between the depression and location in patients with cerebral infarction.Methods Seventy-eight cases of cerebral infarction patients were assessed by HAMD.The subjects were divided into 2 groups.All of them were tested with the same MRI scanner.Results The incidence of depression was 42.3%.There was no significant difference between patients with left-side and right-side cerebral infarction.And there was significant difference between patients with anterior and posterior cerebral infarction.There was significant difference between patients with cortical and hypophloeodal cerebral infarction.Conclusion Patients with anterior cerebral infarction,and cortical cerebral infarction tend to suffer from depression.