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Takayasu arteritis developing during treatment of ulcerative colitis with infliximab
Authors:Yoshiro Horai  Oka Satoru  Samuel Lapalme-Remis  Remi Sumiyoshi  Yoshikazu Nakashima  Takahisa Suzuki  Akitomo Okada  Shin-ya Kawashiri  Kunihiro Ichinose  Mami Tamai  Satoshi Yamasaki  Hideki Nakamura  Fuminao Takeshima  Tomoki Origuchi  Atsushi Kawakami
Affiliation:1. Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan
2. Division of Neurology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
3. Unit of Translational Medicine, Department of Gastroenterology and Hepatology, Nagasaki University, Graduate School of Biomedical Sciences, Nagasaki, Japan
4. Unit of Translational Medicine, Department of Rehabilitation Sciences, Nagasaki University, Graduate School of Biomedical Sciences Biomedical Sciences, Nagasaki, 852-8523, Japan
Abstract:A 22-year-old female with ulcerative colitis that was successfully treated with infliximab (IFX), and remained stable following tapered discontinuation of prednisolone, developed anterior neck pain and elevation of C-reactive protein following her fourth administration of IFX. She was diagnosed with Takayasu arteritis (TA) based on neck ultrasound and computed tomography angiography. This is the first report describing the development of TA during treatment of UC with IFX.
Keywords:Takayasu arteritis  Ulcerative colitis  Infliximab
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