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我院168例抗菌药物致不良反应报告分析
引用本文:朱鹏祥,张麒.我院168例抗菌药物致不良反应报告分析[J].中国药房,2010(46):4392-4394.
作者姓名:朱鹏祥  张麒
作者单位:[1]江苏泰州市人民医院,泰州市225300 [2]南通大学医学院,南通市226001
摘    要:目的:了解我院抗菌药物致不良反应发生特点及规律,为临床用药提供参考。方法:通过对我院2008年1月~2010年3月自发呈报的168例抗菌药物致不良反应报告进行回顾性分析,对引起不良反应的药品种类、给药途径、临床表现以及患者的年龄、性别、不良反应史等方面进行统计、分析。结果:168例抗菌药物致不良反应报告中成年人比例最大,给药途径以静脉滴注为主,主要不良反应为皮肤及其附件损害。结论:临床应加强抗菌药物致不良反应监测,实行个体化给药,减少抗菌药物不良反应的发生。

关 键 词:抗菌药物  不良反应  报告  分析

Analysis of 168 Cases of Antibiotics-induced Adverse Drug Reaction Reported in Our Hospital
ZHU Peng-xiangTaizhou People's Hospital of Jiangsu Province,Taizhou,China ZHANG Qi.Analysis of 168 Cases of Antibiotics-induced Adverse Drug Reaction Reported in Our Hospital[J].China Pharmacy,2010(46):4392-4394.
Authors:ZHU Peng-xiangTaizhou People's Hospital of Jiangsu Province  Taizhou  China ZHANG Qi
Institution:ZHU Peng-xiang(Taizhou People's Hospital of Jiangsu Province, Taizhou 225300, China) ZHANG Qi(Medical School of Nantong University, Nantong 226001, China)
Abstract:OBJECTIVE: To investigate the characteristics and regularity of antibiotics-induced adverse drug reaction (ADR) reported in our hospital and to provide reference for rational use of drugs in the clinic. METHODS: 168 cases of antibiotics-in- duced ADR reported in our hospital during Jan. 2008-Mar. 2010 were analyzed retrospectively in respect of the kind of drugs, routes of administration, clinical manifestation and the age, sex, the history of ADR. RESULTS: Among 168 ADR reports, the adult occupied the largest proportion, the main route of administration was intravenous dripping infusion, the major manifestation of ADR was the damage of skin and its appendants. CONCLUSION: Antibiotics-induced ADR monitoring should be reinforced and individual administration should be implemented to reduce and prevent the occurrence of ADR.
Keywords:Antibiotics  Adverse drug reaction  Report  Analysis
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