| 注射用头孢米诺钠与注射用甲磺酸培氟沙星在0.9%氯化钠注射液中的配伍稳定性 |
| |
| 引用本文： | 王群,庞卫国,丁峰,石庆平,王靖.注射用头孢米诺钠与注射用甲磺酸培氟沙星在0.9%氯化钠注射液中的配伍稳定性[J].中国药房,2010(42):3983-3985. |
| |
| 作者姓名： | 王群 庞卫国 丁峰 石庆平 王靖 |
| |
| 作者单位： | [1]蚌埠医学院第一附属医院药剂科,蚌埠市233004 [2]杭州师范大学医药卫生管理学院,杭州市310036 |
| |
| 摘 要： | 目的:考察注射用头孢米诺钠与注射用甲磺酸培氟沙星在0.9%氯化钠注射液中的配伍稳定性。方法:将注射用头孢米诺钠与注射用甲磺酸培氟沙星加入0.9%氯化钠注射液中,混合均匀后,在25、37℃下于0、1、2、4、6、8h时采用紫外分光光度法测定头孢米诺钠和培氟沙星含量,同时记录外观和pH值变化。结果:0～6h内混合液外观、pH值、头孢米诺钠和培氟沙星的含量、紫外吸收峰形均无显著变化。结论:注射用头孢米诺钠与注射用甲磺酸培氟沙星在0.9%氯化钠注射中可以配伍使用,宜在6h内用完。
|
| 关 键 词： | 注射用头孢米诺钠 注射用甲磺酸培氟沙星 0.9%氯化钠注射液 稳定性 紫外分光光度法 |
Compatibility Stability of Cefminox Sodium for Injection and Pefloxacin for Injection in 0.9% Sodium Chloride Injection |
| |
| WANG Qun,PANG Wei-guo,DING Feng,SHI Qing-pingDept. of Pharmacy,The First Affiliated Hospital of Bengbu Medical College,Bengbu,China WANG Jing.Compatibility Stability of Cefminox Sodium for Injection and Pefloxacin for Injection in 0.9% Sodium Chloride Injection[J].China Pharmacy,2010(42):3983-3985. |
| |
| Authors: | WANG Qun PANG Wei-guo DING Feng SHI Qing-pingDept of Pharmacy The First Affiliated Hospital of Bengbu Medical College Bengbu China WANG Jing |
| |
| Institution: | WANG Qun,PANG Wei-guo,DING Feng,SHI Qing-ping(Dept. of Pharmacy,The First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China) WANG Jing(Medicine and Health Management College,Hangzhou Normal University,Hangzhou 310036,China) |
| |
| Abstract: | OBJECTIVE：To investigate the compatibility stability of Cefminox sodium for injection and Pefloxacin for injection in 0.9% Sodium chloride injection. METHODS：Cefminox sodium for injection and Pefloxacin for injection were added into 0.9% Sodium chloride injection. The contents of cefminox sodium and pefloxacin were determined by UV spectrophotometry at the 0,1st,2nd,4th,6th and 8th hour after mixing at the temperature of 25 ℃ and 37℃. The pH value and appearance of mixture were detected. RESULTS：There were no visible changes within 6 hours in terms of the appearance,pH,forms of peaks of mix- ture. No significant content changes of cefminox sodium and pefloxacin were found under the experiment condition. CONCLUSION：Cefminox sodium for injection and Pefloxacin for injection in 0.9% Sodium chloride injection mixed under the room temperature are compatible and should be used within 6 hours. |
| |
| Keywords: | Cefminox sodium for injection Pefloxacin for injection 0 9% Sodium chloride injection Compatibility UV spectrophotometry |
| 本文献已被 维普 等数据库收录！ |
|
