高血压病患者脉搏波速度与动态脉压的相关性研究

目的探讨高血压病患者脉搏波速度与动态脉压的相关性。方法根据24h平均脉压水平将224例高血压病患者分为3组,对其进行脉搏波速度检测。结果颈-股动脉脉搏波速度(CFPWV)随24h平均脉压升高而升高,颈-桡动脉脉搏波速度(CRPWV)组间差异无统计学意义。CFPWV与诊室脉压(r=0.251,P<0.001)、白昼脉压(r=0.341,P<0.001)、夜间脉压(r=0.301,P<0.001)及24h平均脉压(r=0.338,P<0.001)均呈显著正相关,CRPWV与脉压无显著的相关关系。结论高血压病患者CFPWV与动态脉压密切相关。

Association between Pulse Wave Velocity and Ambulatory Pulse Pressure in Patients with Essential Hypertension

Objective To explore the association between pulse wave velocity and ambulatory pulse pressure in patients with essential hypertension. Methods 224 patients with essential hypertension were enrolled and divided into 3 groups based on the levels of 24 h mean pulse pressure. Carotid-femoral PWV(CFPWV) and carotid-radial PWV(CRPWV) were measured by automatic pulse wave velocity measuring system. Results CFPWV increased with 24 h mean pulse pressure(P﹤0.001), whereas CRPWV did not change significantly. CFPWV was positively and significantly correlated with clinic pulse pressure(r=0.251, P﹤0.001), daytime pulse pressure(r=0.341, P﹤0.001), nighttime pulse pressure(r=0.301, P﹤0.001)and 24 h mean pulse pressure(r=0.338, P﹤0.001). Such relationships were not found with CRPWV. Conclusion CFPWV but not CRPWV closely correlate with ambulatory pulse pressure.