| PVA人工玻璃体的研制及实验研究 |
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| 引用本文： | 牟国营,许吉生,王立群,王本莲,张桔,王会斌. PVA人工玻璃体的研制及实验研究[J]. 山东大学学报(医学版), 1993, 0(4) |
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| 作者姓名： | 牟国营 许吉生 王立群 王本莲 张桔 王会斌 |
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| 作者单位： | 济南市中心医院眼科，济南市中心医院眼科，济南市中心医院眼科，山东省医疗器械研究所，山东省医疗器械研究所，山东省医疗器械研究所 |
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| 基金项目： | 国家科委资助项目，中日科技合作项目 |
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| 摘 要： | PVA人工玻璃体是聚乙烯醇经过过滤、透析、辐照交联和膨润制成的具有三维立体结构的高分子水凝胶。当膨润比为1∶89时,其含水量、屈光指数等理化指标与生体玻璃体相近,小牛血清能良好的渗入其中。兔眼玻璃体置换后观察,PVA人工玻璃体具有良好的组织相融性,术后2个月玻璃体保持透明,术后眼压一直略高于术前,表明此材科是一种有前途的理想的玻璃体代用物。
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| 关 键 词： | 聚乙烯醇 玻璃体 玻璃体置换 兔 |
PREPARATION OF PVA SYNTHETIC VITREOUS AND ITS ANIMAL EXPERIMENTAL STUDY |
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| Mu Guoying,et al. PREPARATION OF PVA SYNTHETIC VITREOUS AND ITS ANIMAL EXPERIMENTAL STUDY[J]. Journal of Shandong University:Health Sciences, 1993, 0(4) |
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| Authors: | Mu Guoying et al |
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| Abstract: | Polyvinyl Alcohol can be made into a 3-dimentional transparenthydrogel(PVA Synthetic vitreous)through the process of filtration,dialysis,irradiation and cross-linking and swelling.When the swelling ratio is 1:89,the water content and refractive index of PVA synthetic vitreous are iden-tical to those of normal vitreous.And bovine serum can diffuse well inside.The results of rabbit vitreous replacement show that PVA synthetic vitreoushas good tissue biocompatibility,remains transparent inside rabbit eyes for2 months and can maintain the intraocu(?)ar pressure a little higher than thatbefore operation.So PVA synthetic vitreous is a potential ideal vitreoussubstitute. |
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| Keywords: | Polyvinyl alcohol Vitreousbody Vitreous replacement Rabbit |
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