| 纳洛酮治疗新生儿缺氧缺血性脑病 |
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| 引用本文： | 许平,马桂荣,吕学云,张勇军,丁登森,任家明. 纳洛酮治疗新生儿缺氧缺血性脑病[J]. 中国新药与临床杂志, 1994, 0(2) |
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| 作者姓名： | 许平 马桂荣 吕学云 张勇军 丁登森 任家明 |
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| 作者单位： | 山东省聊城地区人民医院 |
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| 摘 要： | 新生儿缺氧缺血性脑病６２例，分２组。纳洛酮组３１例（男性２０例，女性１１例）采用常规综合治疗外加用纳洛酮０．２ｍｇ于１０％葡萄糖溶液１００ｍＬ中静脉滴注，隔１ｈ可重复，每日２－３次，共用５－７ｄ。对照组采用相同的常规综合治疗，疗程相同。结果：纳洛酮组治愈率８７％，病死率１３％，对照组依次为６８％和３２％；组间比较Ｐ＜０．０５。未发生不良反应。
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| 关 键 词： | 纳洛酮，新生儿窒息，脑缺血 |
Naloxone in treating hypoxic-ischemic encephalopathy |
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| XU Ping,MA Gui-Rong,LU Xue-Yun,ZHANG Yong-Jun,DING Deng-Sen,REN Jia-Ming. Naloxone in treating hypoxic-ischemic encephalopathy[J]. Chinese Journal of New Drugs and Clinical Remedies, 1994, 0(2) |
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| Authors: | XU Ping MA Gui-Rong LU Xue-Yun ZHANG Yong-Jun DING Deng-Sen REN Jia-Ming |
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| Abstract: | Thirty-one neonates(M 20,F11)with hypoxic-ischemic encephalopathy were given naloxone 0.2 mg in 10% glucose solution 100 mL,iv every hour,twice or three times a day,for 5-7 d as a course in addition to conventional therapy.Another 31 neonates(M 21,F 10) were given routine remedies as control.Results showed that the cure rate and mortality of naloxone group were 87% and 13%;that the control group were 68% and 32%,respectively(P<0.05).No adverse reaction was observed. |
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| Keywords: | naloxone asphyxia neonatorum cerebral ischemia |
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