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Bowel perforation after paediatric orthotopic liver transplantation
Authors:H. Vilca Melendez  V. Vougas  P. Muiesan  P. Andreani  G. Mieli-Vergani  M. Rela  N. D. Heaton
Affiliation:(1) Liver Transplant Surgical Service, King's College Hospital, Denmark Hill, London SE5 9RS, UK Fax: + 44 171 346 3575 e-mail:hector.vilca_melendez@kcl.ac.uk, DK;(2) Department of Child Health, King's College Hospital, Denmark Hill, London SE5 9RS, UK, DK
Abstract:Bowel perforation is a well-recognized complication following orthotopic liver transplantation. Of 194 paediatric liver transplantations performed in our hospital, 13 patients (6.7 %) developed bowel perforation post-transplantation. Contributory factors included previous operation, steroid therapy and viral infection. The incidence was higher in children who underwent transplantation for biliary atresia after a previous Kasai portoenterostomy. Seven patients (53 % of this group) reperforated. Diagnosis may be difficult and a high index of suspicion is needed. Received: 8 December 1997 Received after revision: 17 February 1998 Accepted: 2 March 1998
Keywords:Liver transplantation  intestinal perforation  Intestinal perforation  liver transplantation
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