Bowel perforation after paediatric orthotopic liver transplantation |
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Authors: | H Vilca Melendez V Vougas P Muiesan P Andreani G Mieli-Vergani M Rela N D Heaton |
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Institution: | (1) Liver Transplant Surgical Service, King's College Hospital, Denmark Hill, London SE5 9RS, UK Fax: + 44 171 346 3575 e-mail:hector.vilca_melendez@kcl.ac.uk, DK;(2) Department of Child Health, King's College Hospital, Denmark Hill, London SE5 9RS, UK, DK |
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Abstract: | Bowel perforation is a well-recognized complication following orthotopic liver transplantation. Of 194 paediatric liver transplantations
performed in our hospital, 13 patients (6.7 %) developed bowel perforation post-transplantation. Contributory factors included
previous operation, steroid therapy and viral infection. The incidence was higher in children who underwent transplantation
for biliary atresia after a previous Kasai portoenterostomy. Seven patients (53 % of this group) reperforated. Diagnosis may
be difficult and a high index of suspicion is needed.
Received: 8 December 1997 Received after revision: 17 February 1998 Accepted: 2 March 1998 |
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Keywords: | Liver transplantation intestinal perforation Intestinal perforation liver transplantation |
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