1 780例出院病人抗菌药物应用现状调查

目的:了解某医院抗菌药物使用现状和存在问题。方法:对某院2006年1月份的1780份出院病例进行回顾性调查。对抗菌药物使用率、用药密度,用药种类及构成比,用药时间及联用情况、细菌培养及药敏试验等进行分析。结果:1780例出院患者中,有1379例使用了抗菌药物,抗菌药物使用率为77.47%,其中预防用药占47.50%;只用一种抗菌药物的有234例,占16.97%;使用较多的抗菌药物依次为第3代头孢菌素类(包括抑酶剂联合制剂),氟喹诺酮类,青霉素类(包括抑酶剂联合制剂),硝基咪唑类和大环内酯类;52.57%的患者用药时间<7d;27.41%的患者用药时间>14d;进行药敏试验者仅占全部用药人数的7.11%。结论:住院病人抗菌药物使用中存在使用率高、用药起点高、用药时间长、联用品种多及预防用药比例偏高,细菌培养和药敏试验率低等不合理用药现象。

Investigation of Antimicrobial Applications in 1780 Discharged Patients

Objective: To investigate the problems in the usage of antimicrobial agents in a hospital and provide guidan-ce for the rational use of antimicrobial agents in clinic. Methods: Antimicrobial usage in patients who were discharged from hospital in January,2006 was analysed retrospectively by medical record reviewing. Results: 1 379 of 1 780 discharged patients (77.47%) used antimicrobial agents ,47.50% were for preventive administration;234(16.97%) patients used only1 kind of antimicrobial agent.The commonly used antimicrobial agents were the third generation cephalosporins, quinolones, penicillins, 52.57% of patients used antimicrobial agents for less than 7 days and 27.41% for more than 14 days.Samples from only 7.11% of patients used antimicrobial agents were performed antimicrobial susceptibility test. Conclusions: Some patients used antimicrobial agents irrationally ,detection rates of samples for antimicrobial susceptibillty test was low ,the usage of antimicrobial agents should be paid attention.[