前房容积与白内障超声乳化术后角膜内皮变化的相关性分析

目的探讨白内障超声乳化术前前房容积、前房深度状态与术后角膜内皮细胞变异之间的相关性。方法对46例（60只眼）老年性白内障行白内障超声乳化吸出及人工晶状体植入术。术前以Pentacam三维前房分析仪测定前房容积、前房深度,并分别于术前和术后1周使用非接触型角膜内皮显微镜观察中部角膜内皮细胞的密度变化。结果术前的平均前房容积为（153.43±21.37）mm3,前房深度为（2.72±0.33）mm。术后1周平均中部角膜内皮细胞损失率为（9.27±5.17）%,术前的前房容积与术后1周角膜内皮细胞损失率呈显著负相关（r=-0.703,P〈0.001）,前房深度与术后1周角膜内皮细胞损失率亦呈显著负相关（r=-0.711,P〈0.001）。结论白内障超声乳化吸出人工晶状体植入术后角膜内皮细胞损失率与术前前房空间状态密切相关,Pentacam三维前房分析仪对于前房空间的量化测量为临床评估手术预后提供重要参考。

Analysis the relationship between anterior chamber space and the corneal endothelial change in phacoemulsification

Objective To analyse the relationship between anterior chamber space and the corneal endothelial change in phacoemulsification.Methods Phacoemulsifi-cation and IOL implantation were performed in 60 eyes of 46 patients.The anterior chamber volume and chamber depth were measured by using Pentacam before surgery.Endothelial densities of the mid-cornea were measuredwith noncontact specular microscope before and one week aftersurgery.Results The mean preoperative anterior depth was（2.72±0.33 mm）,the anterior chamber volume was（153.43±21.37）mm3,The corneal endothelial cell lossrate was 9.27%±5.17%.A significant negative correlation existed between the preoperative anterior chamber space and the postoperative corneal endothelial cell loss rate（P0.001）.Conclusion Pentacam,as a new 3-dimensional mathematical model of the anterior segment,is helpful in evaluating the severity of endothelial damage after surgery and can be used to predict the outcome of the cornea.