心室复极化时程的变异及心室复极化时程对RR间期依赖性的研究

心室复极化时程作为反映心室除极和复极时间的重要的电生理参数，越来越受到关注。它受到许多生理和病理因素的影响，在许多心脏疾病中它表现出明显的特征。我们研究了正常人不同年龄组以及正常人和心脏病人心室复极化时程变异(RepolarizationDuration Variability, RDV)和心室复极化时程对RR间期(RTm对RR)依赖性的变化规律。从我们的实验结果看到RDV和RTm对RR依赖性指标均与年龄有关，心脏病人RTm/RR斜率、频域相干性和CV比以及RDV与正常人比较均有非常显著的差异。RDV和RTm对RR依赖性指标将会在临床上评价心脏疾病和功能方面发挥更大的作用。

A Study of Ventricular Repolarization Duration Variability and Dependence of RTm/RR

As an important electrophysiological parameter that reflects cardiac depolarization and repolarization process, ventricular repolarization duration has been drawing growing attention. It is influenced by several physiological and pathological factors and associated with several cardiac diseases. We studied repolarization duration variability (RDV) and dependence of RTm/RR among normal subjects of different age groups, as well as between normal subjects and subjects with cardiac diseases. It was found that RDV and dependence of RTm/RR are related to age. There are significant differences in the slope of RTm/RR, coherence, CV ratio and RDV between normal subjects and subjects with cardiac diseases. The RDV and dependence of RTm/RR can be employed in providing a more useful evaluation of cardiac disease and function in clinical care.