Haemolytic uraemic syndrome and pseudomembranous colitis |
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| Authors: | N. Rooney S. Variend L. S. Taitz |
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| Affiliation: | (1) Department of Pathology, Bristol Royal Infirmary, Marlborough Street, BS2 8HW Bristol, UK;(2) Department of Pathology, Children's Hospital, Western Bank, S10 2TH Sheffield, UK;(3) Department of Paediatrics, Children's Hospital, Western Bank, S10 2TH Sheffield, UK |
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| Abstract: | Two cases of haemolytic uraemic syndrome (HUS) associated with pseudomembranous colitis (PMC) are described. The toxin ofClostridium difficile was detected post mortem in the stool of one patient and the other patient showed a good therapeutic response to oral vancomycin, an antibiotic with established efficacy in the management of PMC. When associated with HUS, PMC is probably an independent specific disease that, in common with many other infections, may activate HUS. |
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| Keywords: | Haemolytic uraemic syndrome Pseudomembranous colitis |
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