四川省200O年犬只携带狂犬病毒及免疫后效果的流行病学调查

目的为进一步预防和控制狂犬病.方法从7个监测点随机采集436份犬只唾液和132份血清,冷冻保存,分别用法国巴斯德诊断试剂盒检测狂犬病毒抗原和抗体.结果在436份唾液标本中,抗原阳性18份,平均阳性率4.13%,带毒率在0～10%之间,最高为宜宾市高县(10%),最低为资中(0),经x2检验,各地区犬只带毒率无显著性差异(P＞0.05).132份血清标本中,抗体阳性仅12份,阳性率9.09%,抗体阳转率最高为双流县(25%),资中县、荣县均为0,经x2检验,无显著性差异(P＞0.05).结论我省监测点犬只携带狂犬病毒普遍存在,有严重的流行隐患.

EPIDEMICAL INVESTIGATION OF DOGS CARRYING RABIES VIRUS AND IMMUNE RESPONSE PROD UCED BY ANTI - RABIES VACCINES IN YEAR 2000 IN SICHUAN PROVINCE

Objective: To investigate epidemiologically the dogs carrying rabies virus for further prophylaxis and control of rabies in Sichuan Province. Methods: 436 canine saliva and 132 serum samples were randomly collected from 7 surveillance spots. They were frozen and presen'ed, then tested with Pasteur diagnostics kit to determine the rabies virus antigens and antibody respectively. Results: The positive saliva samples were 18 out of 436, the average positive rate was 4.13% . The rates of carrying rabies virus vavied between 0 and 10% . The highest district was Gao xian County of Yibin City( 10% ) and the lowest one was Zizhong(0% ) . There was no significant difference with chi - square test( P > 0.05) . The positive serum samples were 12 out of 132, the average positive rate was 9.09% . The positive rates of antibody varied between 0 and 25% . The highest district was Shuangliu county(25%)and the lowest one was Zizhong County. There was no significant difference with chi - square test(P > 0.05) . Conclusion: Dogs carrying rabies virus are existing wildly in the surveillance spots of Sichuan Province. The positive rate of antibody of dogs is low after vaccination. Epidemical hidden danger is severe.