| 线栓法制备大鼠大脑中动脉阻塞模型的体会 |
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| 引用本文： | 冯珂,纪立金. 线栓法制备大鼠大脑中动脉阻塞模型的体会[J]. 辽宁中医杂志, 2013, 0(1): 21-23 |
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| 作者姓名： | 冯珂 纪立金 |
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| 作者单位： | 山东中医药大学;福建中医药大学中医学院 |
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| 基金项目： | 国家自然科学基金面上项目(30973708) |
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| 摘 要： | 线栓法大鼠大脑中动脉阻塞(MCAO)模型被普遍认为是脑缺血标准动物模型。该模型在制备过程中,易受到多重因素的影响。文章从血管解剖位置、插线的制备、切口位置、插线深度及翼腭动脉结扎等角度,对模型塑造过程中发现的现象与问题进行论述。
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| 关 键 词： | 线栓法 大鼠 大脑中动脉阻塞模型 |
Experience of Middle Cerebral Artery Occlusion Model with Suture-Occluded Mechod in Rats |
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| FENG Ke,JI Lijin. Experience of Middle Cerebral Artery Occlusion Model with Suture-Occluded Mechod in Rats[J]. Liaoning Journal of Traditional Chinese Medicine, 2013, 0(1): 21-23 |
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| Authors: | FENG Ke JI Lijin |
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| Affiliation: | 1.Shandong University of Traditional Chinese Medicine,J’inan 250355,Shandong,China; 2.Fujian University of Traditional Chinese Medicine,Fuzhou 350122,Fujian,China) |
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| Abstract: | Middle cerebral artery occlusion model with suture-occluded mechod in rats is considered to be the standard animal model of cerebral ischemia.In the process of preparation,it is susceptible to be influenced by multiple factors.This article discussed the phenomenon and problems discovered in the modeling process,such as vascular anatomic location,preparation of line bolt,incision position,depth of line inserted and ligation of the pterygopalatine artery. |
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| Keywords: | suture-occluded method rats middle cerebral artery occlusion model |
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