Subcutaneous T-cell lymphoma: report of two cases |
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Authors: | Feliks Wsik Tomasz Koodziej Micha Jele Jerzy Pejcz |
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Institution: | Department of Dermatology, University School of Medicine, Wroclaw, Poland;Department of Pathology, University School of Medicine, Wroclaw, Poland;Department of Child Hematology and Oncology, University School of Medicine, Wroclaw, Poland |
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Abstract: | We have seen two patients, a 24-year-old man and a 15-year-old girl, with subcutaneous nodules and fever. The histo-pathological findings in both cases showed a lobular, histiocytic panniculitis with 'bean bag' cells and lymphoid cells identified as immature T-cells. This picture was consistent with subcutaneous T-cell lymphoma associated with cytophagic histiocytic panniculitis. The girl died after 5 months of disease with florid hemophagocytic syndrome; the man was subjected to a course of treatment (CHOP; cyclophosphamide/doxorubicin/vincristine/prednisone) and after 6 months observation his symptoms of nodules and fever disappeared. |
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Keywords: | T-cell lymphoma Panniculitis Cytophagic histiocytic syndrome |
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