壳聚糖非对称多孔膜的制备和性能研究

以可降解壳聚糖为材料，运用浸溃沉淀相分离工艺制备了壳聚糖膜，用扫描电镜观察了膜的微观形态，并研究了聚合物溶液浓度、溶剂蒸发时间等工艺条件对膜孔隙率、溶胀性以及拉伸强度和断裂伸长率等性能的影响。结果表明：该膜具有非对称结构，由致密层、过渡层和疏松多孔层几部分构成；聚合物溶液浓度、溶剂蒸发时间是影响膜结构和性能的重要因素，聚合物溶液浓度增大和溶剂蒸发时间变长都使得膜的孔隙率和溶胀性降低，但却可提高膜的力学性能。

Preparation and Characterization of Asymmetric Porous Chitosan Membrane

A novel kind of guided tissue regeneration (GTR) barrier membrane was fabricated using an immersion-precipitation phase inversion technique with the biodegradable material of chitosan. The morphology of the prepared membrane was described by scanning electronic microscopy. The effects of polymer concentration and solvent evaporation time on the porosity, average pore size, swelling ratio and the mechanical properties as tensile strength and elongation of the membrane were also investigated. (Research) results show that the membrane has an asymmetric structure, which consists of a dense skin layer, a thin transition region and a sponge like porous layer. Polymer concentration and solvent evaporation time are two key factors that have great effect on the structure and the properties of the membrane. Both a bigger polymer concentration and a longer solvent evaporation time result in a lower porosity and a smaller swelling ratio, while tensile strength of the membranes are raised at the same time. This work may be help for the development of a novel kind of GTR barrier membrane material.