高血压药物时间治疗学的临床应用

目的观察高血压患者血压昼夜节律及高血压药物时间治疗的血压控制情况并分析影响因素。方法收集近3年住院高血压患者200例，根据动态血压监测结果将血压昼夜节律分为杓型、非杓型、反杓型及超杓型，按类型进行时间给药，随访2个月进行分析。结果入选患者中，正常血压节律87例，占43．5％；异常血压节律113例，占56．5％，其中非杓型占34．5％，反杓型占20％，超杓型占2％，中青年以正常血压节律为主，老年人以异常血压节律居多，治疗2个月，血压达标率72．5％，有71．68％的异常血压节律转为正常血压节律。结论高血压患者应重视血压节律的检测，强化高血压药物的时间治疗学。

Clinical employ of the hypertensive medicine time treatmentology

Objective To mvestigate circadian blood pressure profile and blood pressure control of the time treatment and its influencing factors in hypertensive patients.Methods 200 cases during the last 3 years were selected,with blood pressure monitoring,circadian blood pressure profile was divided into dipping,non-dipping,reverse-dipping and extreme-dipping,time take medicine accordance with type,2 month observe.Results In all the cases,87(43.5%)showed normal circadian blood pressure profile and 113(56.5%)showed abnormal circadian blood pressure profile(34.5% of non-dipping,20% of reverse-dipping and 2% of extreme-dipping).normal circadian blood pressure profile is more in middle-younger old than older.abnormal circadian blood pressure profile is more in older than it.2 month treatment 72.5% of blood pressure up to the standard,71.68% of abnormal circadian blood pressure are changed normal circadian blood pressure.Conclusion Blood pressure monitoring should be emphasized in hypertensive patients.Time-treatmenology of hypertensive medicine be intensified.