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B-型钠尿肽在舒张性心衰和无症状性心衰中的临床应用价值
引用本文:卜殷中,张大维,刘奇良. B-型钠尿肽在舒张性心衰和无症状性心衰中的临床应用价值[J]. 华中医学杂志, 2005, 29(4): 279-280
作者姓名:卜殷中  张大维  刘奇良
作者单位:200060,上海,上海市普陀区人民医院心内科;200060,上海,上海市普陀区人民医院心内科;200060,上海,上海市普陀区人民医院心内科
摘    要:目的探讨B型钠尿肽测定在慢性舒张性心衰和无症状性心衰中的临床意义。方法35例症状性舒张性心衰和31例无症状性心衰患者测定血浆B型钠尿肽,并另选31例非心衰患者作为对照组测定血浆B型钠尿肽。结果症状性患者的血浆B型钠尿肽同对照组相比明显增高(P<0.05),无症状性心衰患者的血浆B型钠尿肽同对照组相比无明显差异(P>0.05)。结论B型钠尿肽是舒张性心衰敏感而特异的生化指标,临床表现结合心脏超声及B型钠尿肽可以较准确地诊断舒张性心衰。

关 键 词:舒张性心衰  无症状性心衰  B-型钠尿肽
收稿时间:2005-05-08
修稿时间:2005-05-08

Clinical value of B-type natriuretic peptide in diastolic heart failure and asymptomatic heart failure
Bu Yinzhong,Zhang Dawei,Liu Qiliang. Clinical value of B-type natriuretic peptide in diastolic heart failure and asymptomatic heart failure[J]. Central China Medical Journal, 2005, 29(4): 279-280
Authors:Bu Yinzhong  Zhang Dawei  Liu Qiliang
Abstract:Objective To evaluate the clinical significance of B-type natriuretic peptide in chronic diastolic heart failure and asymptomatic heart failure.Methods Plasma B-type natriuretic peptide was determined in 35 patients with symptomatic diastolic heart failure and 31 patients with asymptomatic heart failure. Thirty-one cases of non-heart failure served as control group.Results Levels of plasma B-type natriuretic peptide were increased significantly in symptomatic patients as compared with those in control group (P<0.05). However, there was no significant difference in the levels of B-type natriuretic peptide between asymptomatic patients and controls (P>0.05).Conclusion B-type natriuretic peptide is a sensitive and specific biochemical marker of diastolic heart failure. Combined with B-type natriuretic peptide, symptoms and echocardiography, diastolic heart failure can be diagnosed accurately.
Keywords:Diastolic heart failure Asymptomatic heart failure B-type natriuretic peptide
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