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Distinct Cytokine Release Profiles from Human Endothelial and THP-1 Macrophage-like Cells Exposed to Different Amphotericin B Formulations |
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| Abstract: | Amphotericin B(AmB) formulations, Fungizone, and Amphotec caused substantially greater proinflammatory cytokine release than AmBisome (L-AMB) and Abelcet in TPA differentiated THP-1 macrophages as determined by antibody based protein arrays. Lipopolysaccharide but not AmB induced significant pro-inflammatory cytokines in human endothelial cells. |
| Keywords: | Cytokines Amphotericin B THP-1 HUVEC |