沥水调脂胶囊和舒降之片治疗高胆固醇血症的比较研究

目的 评价沥水调脂胶囊和舒降之片治疗高胆固醇血症的疗效与不良反应。方法 66例高胆固醇血症的病人随机分成沥水调脂胶囊组(A组)和舒降之组(B组);A组33例给予沥水调脂胶囊3粒,po,tid,B组33例给予舒降之10mg,po,qd;疗程均为4周。结果 与治疗前相比,A组胆固醇(TC)降低,有效率为90.90%,甘油三脂(TG)降低,有效率为69.70%;B组TC降低,有效率为93.33%,TG降低,有效率为51.51%;A组和B组疗效间无显著性差异(P>0.05),不良反应发生率两组

Comparison of the Efficacy of LSTZ and Simvastatin in Treatment of Hypercholesterolemia

Objective To evaluate the efficacy and safety of LSTZ and simvastatin of hypercholesterolemia.Method 66 patients with primary hypercholesterolemia were randomly divided into two groups. Groups A(n=33) was treated with LSTZ 1.05 g,po,tid×4 wk..Group B(n=33) was treated with simvastatin 10 mg,po.qd×4 wk.Result The efficaious ratio on TC descend are 90.90% and 93.90% for group A and B respectively, on TG descend are 69.70 and 51.51% for group A and B respectively, There are on significant difference between the two groups (P>0.05). The adverse reactions occurrd respectively 3.3% and 12.1% between A and B (P<0.01). Conclusion LSTZ is effective in treatment of hypercholesterolemiawith simvastatin.