Breath Hydrogen Test in the Diagnosis of Environmental Enteropathy in Children Living in an Urban Slum |
| |
Authors: | Jairo César dos Reis Mauro Batista de Morais Carlos Alberto Garcia Oliva Ulysses Fagundes-Neto |
| |
Institution: | (1) Division of Pediatrics, University of Marília, Marilia, Brazil;(2) Federal University of Sao Paulo, Sao Paulo, Brazil;(3) Rua Pedro de Toledo 441, 04039-031 Sao Paulo, SP, Brazil |
| |
Abstract: | The aim of this study was to evaluate the breath hydrogen test in the diagnosis of small intestine bacterial overgrowth associated
with asymptomatic environmental enteropathy in children living in an urban slum. Fifty school-age children living in a slum
and 50 children who attended a private health clinic in the same town were included in the study. Breath hydrogen test was
carried out after the administration of lactulose or glucose on two different days. Bacterial overgrowth was diagnosed when
the hydrogen concentration increased more than 20 ppm in a sample collected for up to 60 min. Production of hydrogen was greater
after the ingestion of lactulose than after the ingestion of glucose. Bacterial overgrowth was noted in 37.5% of the children
living in the slum and in 2.1% of the control group (P < 0.001). The children living in the slum presented a higher proportion of bacterial overgrowth when lactulose was used in
the breath hydrogen test. |
| |
Keywords: | Breath hydrogen test Environmental enteropathy Glucose Lactulose Children Small intestine bacterial overgrowth |
本文献已被 PubMed SpringerLink 等数据库收录! |