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| 盐酸曲马多分子印迹聚合物膜电极的制备及应用 | |
| 引用本文： | 贾评,孙亚军,冯玉枝,修荣. 盐酸曲马多分子印迹聚合物膜电极的制备及应用[J]. 中国医药工业杂志, 2010, 41(4) |
| 作者姓名： | 贾评 孙亚军 冯玉枝 修荣 |
| 作者单位： | 1. 河北北方学院第二附属医院药剂科,河北宣化,075100 2. 河北省廊坊市中医院药剂科,河北廊坊,065000 3. 河北省沧州市人民医院,河北沧州,061001 4. 河北医科大学药学院,河北石家庄,050017 |
| 基金项目： | 河北省科技厅重点资助项目 |
| 摘 要： | 介绍了盐酸曲马多分子印迹聚合物离子选择性电极的制备、特性及应用.该电极在1.0×10~(-6)～1.0×10~(-2)mol/L范围内表现Nernst响应,斜率为30.4mV/pc,检测限为6.3×10~(-7)mol/L,回收率为97%～101%. |
| 关 键 词： | 分子印迹聚合物 盐酸曲马多 离子选择性电极 聚氯乙烯膜 |
Preparation and Application of Traraadol Hydrochloride Electrode Based on Films of Molecularly Imprinted Polymers |
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| Abstract: | A molecular imprinting polymer membrane electrode of tramadol hydrochloride was prepared, characterized and used in pharmaceutical analysis. The electrode exhibits Nernst response in the concentration range of 1.0×10~(-6)-1.0×10~(-2)mol/L. The slope was 30.4 mV/pc and the limit of detection was 6.3×10~(-7) mol/L. The recoveries of tramadol hydrochloride were 97%-101%. |
| Keywords: | molecular imprinting polymer tramadol hydrochloride ion-selective electrode PVC membrane |
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