急性脑出血治疗中尼膜同的应用研究

目的 观察尼膜同治疗急性脑出血的临床疗效。方法 应用前瞻性随机单盲方法,对１８２例经ＣＴ证实的急性脑出血病人,在起病７２小时内随机分为尼膜同和甘露醇组（尼膜同组）及单纯甘露醇组（对照组）,采用神经功能缺损程度积分差及ＣＴ上血肿吸收率为指标,比较两组疗效。结果 尼膜同组在各个时点上神经功能缺损的平均减少分数以及ＣＴ上血肿吸收率均优于对照组。结论 尼膜同是治疗急性脑出血的一种安全、有效的药物。

A application study on nimotop in the treatment of acute intracerebral hemorrhage

Objective To observe the clinical therapeutic effectiveness of nimotop in acute intracerebral hemorrhage. Methods With the prospective random single blind method, 182 patients with acute intracerebral hemorrhage who were confirmed by CT scan randomly accepted the treatment of nimotop or pure mannitol within 72 hours of the hemorrhage onset. The two groups were compared with the indexes of the score difference of neurological functional defect and the hematoma absorptive rate. Results The average decreased score of neurological functional defect with treatment of nimotop at each time point and the hematoma absorptive rate were better than that in the control group. Conclusions Nimotop was a safe and effective drug in the treament of acute intracerebral hemorrhage.