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Donor-Transmitted Bacterial Infection in Deceased Donor Liver Transplantation: Experience of Southern Taiwan Medical Center
Authors:T.-L. Lin  S.-C. Kuo  C.-H. Yeh  Y.-C. Chan  Y.-H. Lin  W.-F. Li  C.-C. Yong  Y.-W. Liu  S.-H. Wang  C.-C. Lin  C.-C. Wang  C.-L. Chen
Affiliation:Liver Transplant Center, Departments of Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan
Abstract:

Background

Bacterial Infection is the most important source of mortality and morbidity in liver transplantation recipients. Donor transmitted bacterial infection is rare but one of the most important infection sources. This kind of infection is difficult to identify, causing treatment dilemma.

Patients and Methods

In this article, we retrospectively reviewed our deceased donor liver transplants performed from January 2014 to December 2016. Forty-two recipients in Kaohsiung Chang Gung Memorial Hospital receiving liver grafts from 35 deceased liver donors were evaluated. The demography, donor transmitted infection, and outcomes were evaluated.

Result

Two patients had probable donor transmitted bacterial infection and 1 patient died of suspected transmitted infection.

Conclusion

Early identification of donor infection and adequate antibiotic treatment for the donor and recipient are the keys to preventing donor transmitted bacterial infection. Donor infection is not an absolute contraindication for organ donation in the area of organ shortage. Organ procurement organizations or similar authorities may establish the platform for sharing the data about donor and recipient infections.
Keywords:Address correspondence to Chih-Chi Wang   MD   Liver Transplant Program   Department of Surgery   Kaohsiung Chang Gung Memorial Hospital   and Chang Gung University College of Medicine   123 Ta-Pei Road   Niao-Sung   Kaohsiung 833   Taiwan. Tel: +886-975056202   Fax: +886-7-735-4309.
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