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Chemotherapy advances in locally advanced head and neck cancer |
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| Authors: | Peter Georges Kumar Rajagopalan Chady Leon Priya Singh Nadir Ahmad Kamyar Nader Gregory J Kubicek |
| Affiliation: | Peter Georges, Kumar Rajagopalan, Chady Leon, Priya Singh, Kamyar Nader, Department of Medical Oncology, Cooper University Hospital, Camden, NJ 08103, United StatesNadir Ahmad, Department of Otolaryngology, Cooper University Hospital, Camden, NJ 08103, United StatesGregory J Kubicek, Department of Radiation Oncology, Cooper University Hospital, Camden, NJ 08103, United States |
| Abstract: | The management of locally advanced unresectable head and neck squamous cell cancer (HNSCC) continues to improve. One of the major advances in the treatment of HNSCC was the addition of chemotherapy to radiation in the treatment of non-surgical patients. The majority of the data regarding chemotherapy in HNSCC involve cisplatin chemotherapy with concurrent radiation. However, several new approaches have included targeted therapy against epidermal growth factor receptor and several recent studies have explored the role of induction chemotherapy in the treatment of HNSCC. The purpose of this article is to provide an overview of the role of chemotherapy in the treatment of locally advanced HNSCC. |
| Keywords: | Head and neck cancer Chemotherapy Induction |
| 点击此处可从《World journal of clinical oncology》浏览原始摘要信息 | |