阿奇霉素与头孢呋辛治疗儿童呼吸道感染的疗效比较

目的比较阿奇霉素与头孢呋辛治疗儿童呼吸道感染的疗效。方法选取2017年4月至2019年4月我院收治的90例呼吸道感染患儿,随机分为两组各45例。对照组患儿予以静脉滴注头孢呋辛钠治疗,观察组患儿予以静脉滴注阿奇霉素治疗,两组均治疗5 d,比较两组的治疗效果。结果观察组和对照组的治疗总有效率比较,差异无统计学意义(95.56%vs.93.33%,P>0.05)。两组治疗前后的CRP、PCT水平均无统计学差异(P>0.05)。观察组和对照组的不良反应发生率比较,差异无统计学意义(8.89%vs.13.33%,P>0.05)。观察组的体温恢复正常时间、咳嗽消失时间、气促消失时间、湿啰音消失时间均显著短于对照组(P<0.05)。结论阿奇霉素与头孢呋辛治疗儿童呼吸道感染的疗效显著,安全性高;阿奇霉素可更迅速地改善患儿的临床症状。

Comparison on the Curative Effects of Azithromycin and Cefuroxime in the Treatment of Children with Respiratory Tract Infection

Objective To compare the curative effects of azithromycin and cefuroxime in the treatment of children with respiratory tract infection.Methods 90 children with respiratory tract infection in our hospital from April 2017 to April 2019 were selected and randomly divided into two groups equally.The control group was treated with cefuroxime sodium through intravenous drip,and the observation group was treated with azithromycin through intravenous drip.Both groups were treated for 5 d,and the curative effects of two groups were compared.Results No significant difference was found in the total effective rate of treatment between the observation group and the control group(95.56%vs.93.33%,P>0.05).Before and after treatment,no statistical difference was found between two groups in the levels of CRP and PCT(P>0.05).No significant difference was found in the incidence of adverse reactions between the observation group and the control group(8.89%vs.13.33%,P>0.05).The recovery time of body temperature,disappearance time of cough,disappearance time of shortness of breath and disappearance time of moist rale in the observation group were significantly shorter than those in the control group(P<0.05).Conclusions Both azithromycin and cefuroxime have obvious efficacy and high safety in the treatment of children with respiratory tract infection,while azithromycin can improve the clinical symptoms of children more quickly.