| 一阶导数紫外分光光度法测定茶碱的血药浓度 |
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| 引用本文： | 肖桂珍,罗顺德.一阶导数紫外分光光度法测定茶碱的血药浓度[J].中国药师,1998,1(2):80-81. |
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| 作者姓名： | 肖桂珍 罗顺德 |
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| 作者单位： | 广东省珠海市人民医院，湖北医科大学药学系，湖北医科大学药学系，湖北医科大学药学系 519000 |
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| 摘 要： | 采用一阶导数紫外分光光度法进行茶碱血药浓度测定,此法灵敏度高,专一性强,线性良好(r=0.9999,回收率较高,变异性小(RSD<5％)。用于临床茶碱血药浓度监测,方法简便准确,并收到满意效果。
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| 关 键 词： | 导数光谱 茶碱 血药浓度 |
Determination of Theophylline in Human Serum by First Order Derivative UV-Spectrophotometry Method |
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| Xiao Guizhen,Luo Shunde,Zhang Xianzhou,et al Zhuhai People''s Hospital,Zhuhai,Guangdong,P.R.China.Determination of Theophylline in Human Serum by First Order Derivative UV-Spectrophotometry Method[J].China Pharmacist,1998,1(2):80-81. |
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| Authors: | Xiao Guizhen Luo Shunde Zhang Xianzhou Zhuhai People's Hospital Zhuhai Guangdong PRChina |
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| Institution: | Xiao Guizhen,Luo Shunde,Zhang Xianzhou,et al Zhuhai People's Hospital,Zhuhai 519000,Guangdong,P.R.China |
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| Abstract: | The theophylline concentration by a first order derivative UV-spectrophotometry in human serum was determined. The method had advantage of higher sensitivity, stronger specificity, and better linearity (r=0.999 9). The rate of recovery was higher (total CV<5%), the variability was less. This is a better examining method for clinical theophylline serum concentration monitoring, and being simple and presise. |
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| Keywords: | First order derivative spectrophotometry Theophylline Monitoring of serum drug concentration |
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