SARS患者合并肺纤维化的影像学随访

目的探讨SARS患者并发肺纤维化的程度和发生率.方法对确诊的44例SARS患者进行影像学随访观察,包括摄胸部X线及CT扫描检查.结果44例SARS患者中,24例在住院时期有不同程度的肺部纤维化改变,其中19例重症病例中15例出现肺纤维化,25例普通型中9例并发肺纤维化(P＜0.05).出院时,12例(27%)存在肺纤维化.随访1个月、3个月、6个月及12个月时,分别有5例(11%)、3例(6%)、2例(4%)及2例(4%)两肺见纤维条索状影.结论肺纤维化是SARS患者较常见的并发症,重症较普通型者易发生肺纤维化,而且程度较重,吸收慢.

Imaging follow-up of SARS patients complicated with pulmonary fibrosis

Objective To explore the rate of occurrence and extent of pulmonary fibrosis in SARS patients. Methods A one year imaging follow up on 44 SARS patients was performed, including frontal and lateral chest X ray films, frontal X ray films of pelvis and CT scanning. Results All the 44 SARS patients, 24 cases were revealed fibrotic changes of various extent in the lungs while staying in the hospital, among which fibrosis of various extent of the lungs were found in 15 of 19 severe SARS, while in nine of 25 common type of SARS patients ( P <0.05). At time of discharge, 12 patients (27%) had existence of fibrosis in lungs. After a follow up in one month, five SARS patients (11%) showed presence of shadows of fibrotic cords in both lungs of different calibers, three (6%) after three months, and two (4%) after 6-12 months. Conclusion Pulmonary fibrosis is a commonly seen complication in SARS patients. It is more apt to occur in severe SARS patients than in common type of SARS patients. Severe SARS patients complicated with pulmonary fibrosis showed a higher severity marked by more slowly absorptive process.