| 失血性与内毒素性休克家兔血浆纤维连接蛋白含量的动态变化 |
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| 引用本文： | 金惠铭,郭福花,陈达信. 失血性与内毒素性休克家兔血浆纤维连接蛋白含量的动态变化[J]. 中国病理生理杂志, 1987, 0(3) |
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| 作者姓名： | 金惠铭 郭福花 陈达信 |
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| 作者单位： | 上海医科大学病理生理学教研室(金惠铭，郭福花)，上海医科大学病理生理学教研室(陈达信) |
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| 摘 要： | 在失血性与内毒性休克家兔中,利用免疫单扩和双扩法分别测定家兔休克前后不同时间血浆内Fn含量。结果表明,在失血性休克中,休克30分钟时,血浆内Fn有显著性下降,以后随着休克的发展,持续降低。休克30分钟时将血液回输.血压恢复,Fn含量也随之上升。在内毒素性休克中,休克30分钟时,与休克前比较,血浆Fn含量有显著性的升高,休克60分钟时,血浆Fn含量显著降低,后者60分钟变化与失血性休克相同。对上述变化可能发生机制进行了讨论。
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| 关 键 词： | 休克 出血性 休克 脓毒性 纤维连接素类 输血 兔 |
Studies on the changes of fibronectin content in rabbits of hemorrhagic and endotoxic shock |
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| Jin Hui-Ming,et al. Studies on the changes of fibronectin content in rabbits of hemorrhagic and endotoxic shock[J]. Chinese Journal of Pathophysiology, 1987, 0(3) |
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| Authors: | Jin Hui-Ming et al |
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| Affiliation: | Jin Hui-Ming,et al Department of Pathophysiology,Shanghai Medical University,Shanghai |
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| Abstract: | The changes of plasma Fn content in rabbits of hemorrhagic and endotoxic shock has been assayed by means of single and double immunodiffusion tests. The results showed that Fn level significantly declined at 30 minutes after hemorrhagic shock and remained at low level with development of shock. But in the rabbitns transfused at 30 minutes after shock Fn level turned to normal as blood pressure increased. Fn content was significantly elevated at 30 minutes and significantly decreased at 60 minutes after endotoxic shock. The possible pathophysiologic and clinical significance of these changes was disscussed. |
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| Keywords: | hemorrhagic Shock septic Fibronectins Blood transfusion Rabbits |
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