The effect of percutaneous coronary intervention in patients suffering from ST-segment elevation myocardial infarction complicated by out-of-hospital cardiac arrest on 30 days survival |
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Authors: | Christoph Weiser,Christoph Testori,Fritz Sterz,Andreas Schober,Mathias Stö ckl,Peter Stratil,Christian Wallmü ller,David Hö rburger,Alexander Spiel,Istepan Kü rkciyan,Clemens Gangl,Harald Herkner,Michael Holzer |
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Affiliation: | 1. Department of Emergency Medicine, Medical University of Vienna, Austria;2. Department of Cardiology, Medical University of Vienna, Austria |
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Abstract: | Aim of the studyTo question the beneficial effects of the recommended early percutaneous coronary intervention (PCI) after out-of-hospital cardiac arrest on 30-day survival with favourable neurological outcome.MethodsProspectively collected data of 1277 out of hospital cardiac arrest patients between 2005 and 2010 from a registry at a tertiary care university hospital were used for a cohort study.ResultsIn 494 (39%) arrest patients ST-segment elevation was identified in 249 (19%). Within 12 h after restoration of spontaneous circulation catheter laboratory investigations were initiated in 197 (79%) and PCI in 183 (93%) (78% got PCI in less than180 min). Adjustment for a cumulative time without chest compressions <2 min, initial shockable rhythm, cardiac arrest witnessed by healthcare professionals, and a higher core temperature at time of hospitalization reduced the effect of PCI on favourable neurological outcome at 30 days (OR 1.40; 95% CI, 0.53–3.7) compared to the univariate analysis (OR 2.52; 95% CI, 1.42–4.48).ConclusionThis cohort study failed to demonstrate the beneficial effects of PCI as part of post-resuscitation care on 30-day survival with a favourable neurological outcome. |
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Keywords: | Angiography Cardiopulmonary resuscitation Catheterization Heart arrest |
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