黄芪注射液联合磷酸肌酸钠对病毒性心肌炎的疗效及其对患儿血浆超敏C反应蛋白和N末端B型脑钠肽的影响

目的探讨黄芪注射液联合磷酸肌酸钠治疗病毒性心肌炎的疗效及其对患儿血浆超敏C反应蛋白（hs．CRP）和N末端B型脑钠肽（NT—proBNP）的影响。方法将80例病毒性心肌炎患儿按照数字表法随机分为观察组40例和对照组40例。对照组采用常规治疗，观察组在常规治疗的基础上加用黄芪注射液和磷酸肌酸钠。两组均治疗14d。治疗前后测定患儿血浆hs—CRP和NT-proBNP。结果观察组总有效率为97．5％，高于对照组的85．0％（x2=3．88，P〈0．05）。两组患者治疗后血清hs-CRP，NT—proBNP均有明显降低（均P〈0．05），且观察组降低更明显（均P〈0．05）。结论黄芪注射液联合磷酸肌酸钠治疗病毒性心肌炎疗效明确，且可以降低病毒性心肌炎患儿血浆hs—CRP和NT—proBNP的表达。

The effect of astragali injection combined with creatine phosphate in the treatment of viral myocarditis and its influence on plasma high sensitivity C-reactive protein and N-terminal pro-B-type brain natriuretic pep-tide

Objective To explore the effect of astragali injection combined with creatine phosphate in the treatment of children with viral myocarditis and its influence on plasma high sensitivity C-reactive protein（hs-CRP） and N-terminal pro-B-type brain natriuretic peptide （NT-proBNP）. Methods According to the digital table,80 chil- dren with viral myocarditis were randomly divided into the control group （40 cases） and the observation group（40 ca- ses）. The children in the control group were treated through the conventional treatment, while the children in the ob- servation group were treated by astragali injection plus creatine phosphate injection. They were all treated for 14 days. The plasma hs-CRP and NT-proBNP levels were detected before and after treatment. Results The total effective rate of the observation group was 97.5%, which was higher than that of the control group （ 85.0% ） （ X2 = 3.88, P 〈 0. 05 ）. The plasma hs-CRP and NT-proBNP levels of the two groups were decreased after treatment （ all P 〈 0.05 ） , and those of the observation group were lower than the control group （ all P 〈 0.05 ）. Conclusion Astragali injection combined with creatine phosphate in the treatment of children with viral myoearditis has good effect, and can decrease the plasma hs-CRP and NT-proBNP levels.