99mTc右旋糖酐的直肠淋巴引流显像及临床应用

目的 探索正常人经肛门镜直肠粘膜下核素注射后,淋巴显像时间,正常淋巴引流图谱及直肠癌患者术前淋巴结转移的评估方法。方法 １ｍｌ＾９９ｍＴｃ右旋糖酐作为巴显像剂,对３７例正常人及１６例直肠癌患者经肛门镜直肠粘膜下注射,分别于注射后１,２,３小时采用ＴＯＳＨＩＢＡＧＣＡ９０１Ａ型ＳＰＥＣ机显像,获得正常人及直肠癌患者的核素淋巴引流闪烁图谱。结果 在正常人直肠淋巴引流显像中均显示向头侧的淋巴引流链,３小

Lymphoscintigraphy: evaluating lymphatic spread of rectal cancer

Objective To investigate lymphatic drainage of rectal and lymphatic spread of rectal cancer. Methods Rectal endoscopic lymphoscintigraphy was performed in 37 volunteers and 16 patients. One millilitre dextran marked with 99m Tcwas injected bilaterally into submucosa of the rectum through rectal endoscopy. 1,2,3 hours after the injection, rectal lymphoscintigraphy was registered with a computerized gamma camera(TOSHIBA GCA901A). Results Lymphoscintigraphy in control subjects showed upward epirectal and pararectal nodes. The average number of the nodes was 12 three hours after the injection. Compared with histological node examination in all patients operated upon for rectal cancer, rectal endoscopic lymphoscintigraphy showed a sensitivity of 97 1%,a specificity of 75 0%, an overall accuracy of 87 5%, a false positivity of 25 0%, and false negativity of 8 3%. Conclusion The method is better for evaluating lymphatic spread of rectal cancer before operation.