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重楼道地性研究进展
引用本文:王嘉乐,杨青淑,江媛,尚明越,杨燕,段宝忠.重楼道地性研究进展[J].中草药,2022,53(8):2572-2581.
作者姓名:王嘉乐  杨青淑  江媛  尚明越  杨燕  段宝忠
作者单位:大理大学药学院, 云南 大理 671000;云南省科学技术院, 云南 昆明 650051
基金项目:国家自然科学基金项目(31860080);云南省重大科技专项(202002AA100007);云南省兴滇英才支持计划(YNWR-QNBJ-2020251);云南省院士专家工作站(202205AF150026,202105AF150053)
摘    要:从重楼的本草考证、植物学、药材性状、遗传变异、化学成分、药理作用等方面,对重楼道地性研究现状进行了综述。研究发现历代本草所记载的“蚤休”为七叶一枝花Paris polyphylla var.chinensis(华重楼),各产地质量差异不明显;本草记载的“重楼”为云南重楼P.polyphylla var.yunnanensis(滇重楼),其道地产区为西南地区,尤以云南为佳。鉴于植物形态、遗传学和相关文献研究结果,建议将重楼的植物基原的中文学名修订为滇重楼和华重楼;不同产地的滇重楼及华重楼在皂苷成分、脂溶性成分、氨基酸、无机元素含量和遗传上均显示出一定的差异,重楼药材质量受产地和种质的影响较大,筛选优质重楼品种并在适宜产区规范栽培,是实现重楼品质稳定的基础。

关 键 词:重楼  道地药材  化学成分  遗传变异  药理作用
收稿时间:2021/10/9 0:00:00

Geo-herbalism study of Paridis Rhizoma
WANG Jia-le,YANG Qing-shu,JIANG Yuan,SHANG Ming-yue,YANG Yan,DUAN Bao-zhong.Geo-herbalism study of Paridis Rhizoma[J].Chinese Traditional and Herbal Drugs,2022,53(8):2572-2581.
Authors:WANG Jia-le  YANG Qing-shu  JIANG Yuan  SHANG Ming-yue  YANG Yan  DUAN Bao-zhong
Institution:College of Pharmaceutical Science, Dali University, Dali 671000, China;Yunnan Provincial Academy of Science and Technology, Kunming 650051, China
Abstract:This review summarizes the information about the textual research of herbalism, botany, genetic study, chemical components, and pharmacological activities of Paridis Rhizoma. Herein, we focus on the following views: Firstly, according to the records in many ancient Chinese medical books, Paris polyphyllavar.chinensiswas historically called Zao Xiu; And they mentioned the minor differences in restorative materials produced from diverse regions. P. polyphyllavar.yunnanensiswas historically named Chonglou, considering southwest China as the Dao-di region; Meanwhile, it mainly has a kind of Dao-di herbs in Yunnan. Secondly, given the results of plant morphology and genetic research, the Chinese name of original plants of Paridis Rhizoma are revised to Dianchonglou and Huachonglou. Thirdly, there are significant differences between the regions of P. polyphyllavar.yunnanensisandP. polyphyllavar.chinensis,including Paris saponins, liposoluble, amino acid, inorganic element, and genetic diversity. Both areas and germplasm contribute to the quality of the herbal medicine produced. The quality stability of Paridis Rhizomadepends on screening high-quality Paridis Rhizoma germplasm and standard cultivation in suitable regions.
Keywords:Paridis Rhizoma  Dao-di herbs  chemical components  genetic study  pharmacological activity
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