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快中子及混合线照射人成骨肉瘤 OS-732 细胞系的实验观察
引用本文:冯林春,马林,黄靖香,王迎选,孙明学,杨东,唐锦华. 快中子及混合线照射人成骨肉瘤 OS-732 细胞系的实验观察[J]. 军医进修学院学报, 2004, 25(3): 229-230
作者姓名:冯林春  马林  黄靖香  王迎选  孙明学  杨东  唐锦华
作者单位:1. 解放军总医院,放疗科,北京,100853
2. 解放军总医院,骨研所
3. 中科院,高能物理所,北京,100039
基金项目:国家攀登计划B项目(1995-01-1)
摘    要:目的:观察快中子及光子对人成骨肉瘤细胞系OS-732的杀伤作用。方法:用快中子、光子及混合射线照射OS-732细胞系,检测各组细胞受照射后的集落形成率。结果:单次照射后第10天,混合线组对该细胞系集落形成的抑制作用明显弱于单中子及单光子组。结论:单次照射后第10天,单纯快中子及单纯光子对该细胞系集落形成的抑制作用明显强于混合线组,对临床上应用快中子治疗骨肉瘤有一定指导意义。

关 键 词:快中子 成骨肉瘤 OS-732细胞系 实验 光子 混合射线 放射疗法
文章编号:1005-1139(2004)03-0229-02
修稿时间:2003-09-10

Experimental study on human osteosarcoma OS-732 cell line irradiated combined fast neutron with photon
FENG lin-chun,MA lin,HUANG jing-xiang,WANG ying-xuan,SHUN ming-xue,YANG dong,TANG jin-hua. Experimental study on human osteosarcoma OS-732 cell line irradiated combined fast neutron with photon[J]. Academic Journal of Pla Postgraduate Medical School, 2004, 25(3): 229-230
Authors:FENG lin-chun  MA lin  HUANG jing-xiang  WANG ying-xuan  SHUN ming-xue  YANG dong  TANG jin-hua
Abstract:Objective:To observe the injury of OS-732 cell line caused by radiation combined fast neutron with photon. Methods: We tested the clone forming rate of the OS-732 cell line after irradiated by fast neutron,photon and the mixed beam(fast neutron plus photon). Results:The inhibition effect of the clone forming was weaker in the groups of mixed beam than that in the group of fast neutron and photon alone after 10 days. Conclusion:The killing effect was powerful to the OS-732 cell line in the fast neutron alone group and photon alone after 10 days. The studies provide an experimental research for the treatment of osteosarcoma.
Keywords:osteosarcoma  OS-732 cell line  fast neutron  radiationtherapy
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