中西医结合治疗中晚期结肠癌61例

目的:观察中药扶正消积汤联合化疗药物治疗中晚期结肠癌的临床疗效.方法:将病理确诊的中晚期结肠癌患者91例随机分为两组,对照组30例,采用FOLFOX方案化疗治疗组61例,化疗方案同对照组,同时配合中药扶正消积汤,早晚各服150 mL.两组均采用相同止吐等对症处理方案.结果:近期疗效:治疗组全部缓解(CR)9例(14.8％),部分缓解(PR)22例(36.1％),有效率50.8％；对照组CR 4例(13.3％),PR 10例(33.3％),有效率46.7％.两组比较统计学无显著性差异.对治疗后外周血象、体力(KPS)、免疫功能变化观察比较,治疗组能减轻化疗对外周血象、免疫功能的影响,提高KPS评分,差异有显著性意义(P ＜0.05,P＜0.01).结论:扶正消积汤配合化疗可以减轻化疗副作用、改善生活质量、提高治疗效果.

Clinical Observation of Combine Traditional Chinese and Western Medicine Treatment of 61 Patients with Advanced Colon Cancer

Objective: Observed Fuzheng Xiaoji decoction combined with chemotherapy drugs clinical efficacy for the treatment of advanced colon cancer. Method: Pathological diagnosis of 91 patients with Advanced colon cancer were randomLy divided into two groups,the control group of 30 patients,FOLFOX chemotherapy alone;treatment group,61 cases,FOLFOX chemotherapy with the control group,in conjunction with Fuzheng Xiaoji decoction,150 mL of morning and evening services.Both groups were given the same antiemetics and symptomatic treatment program. Result: Recent efficacy:treatment group complete remission(CR) 9 patients (14.8%),partial remission(PR) 22 cases of (36.1%),50.8% efficiency;CR 4 patients of the control group (13.3%),PR in 10 patients (33.3%),46.7% efficiency.The two groups was statistically no significant difference.Peripheral blood after treatment,observation and comparison of physical (KPS),changes in immune function,the treatment group can reduce the impact of chemotherapy on the peripheral blood,immune function,KPS score,the difference was statistically significant (P<0.05, 0.01). Conclusion: Fuzheng Xiaoji Decoction combined with chemotherapy can reduce the side effects of chemotherapy, and to improve the quality of life, improve the therapeutic effect.