数字化放射成像与普通X线诊断肺内单发结节的ROC曲线评价

目的比较数字化放射成像(DR)和普通X线对肺内单发结节的诊断价值。方法选取30例有肺部单发结节和30例无肺内结节的病例,所有肺结节病灶均经CT和病理学证实。分别摄取普通X线胸片和DR,4位高年资医生和4位低年资医生分别对两组影像资料进行评价,结果采用受试者工作特征(ROC)曲线进行统计分析。结果(1)在发现肺内单发结节方面:对高年资医生来说,DR组的ROC曲线下面积(Az=0.838)大于普通胸片组(Az=0.816)(P<0.05);对低年资医生来说,DR组的ROC曲线下面积(Az=0.842)大于普通胸片组(Az=0.712)(P<0.05);(2)在判断肺内单发结节的良恶性方面,两组无显著差异(P=0.272)。结论DR在发现肺内单发结节方面优于普通胸片,而在判断良恶性方面两者差别不大。

Comparison of digital radiography and conventional X-ray in the diagnosis of solitary pulmonary nodule with receiver operating characteristic analysis

Objective To compare digital radiographs with conventional radiographs in the detection of solitary pulmonary nodules. Methods Thirty patients with solitary pulmonary nodule and 30 cases without pulmonary nodules were enrolled in the study. The existence of solitary pulmonary nodule was confirmed by chest computed tomography (CT) as well as biopsy. All patients examined by both digital radiography (group A) and conventional radiographs (group B) were reviewed by four experienced chest radiologists and four residents. Assessment was performed with receiver operating characteristic (ROC) analysis of the images in both groups. Results(1) Observer performance of the experienced radiologists in group B (Az=0.838) was superior to that in group A (Az=0.816) (P<0.05) in detection of solitary pulmonary nodule. For the residents, observer performance in group B (Az=0.842) was superior to that in group A (Az=0.712) (P<0.05). (2) There was no difference between the two groups (P=0.272), for the judgement of benign or malignant solitary pulmonary nodule. Conclusions Digital radio- graphs is superior to conventional radiographs in detection of solitary pulmonary nodule. However, there was no significant differences in discrimination between benign and malignant solitary pulmonary nodules in the two groups.