老年骨质疏松症的防治策略及进展

随着人口老龄化,老年性骨质疏松症在世界范围内患病率逐渐增高.其主要后果是骨质疏松性骨折,对个人、家庭及社会影响巨大.通过国际骨质疏松基金会骨质疏松一分钟测试题以及亚洲骨质疏松自我筛查差工具可以初步发现骨质疏松高危人群.诊断需依据脆性骨折病史或骨密度测定,并要除外继发性骨质疏松的各种原因.治疗包括生活方式调整,骨骼健康基本补充剂以及抗骨质疏松药物治疗,本文也比较了各类抗骨质疏松药物的有效性、安全性及方便性,并介绍了抗骨质疏松的各类新药.

Control strategy and progress of senile osteoporosis

With the poplation aging, the prevalence of senile osteoporosis is gradually increased all over the world. Its main consequence, osteoporotic fractures, exerts greatly impact on individuals, families and society. High-risk populations for osteoporosis could be preliminarily screened out by using International Osteoporosis Foundation (IOF) one minute questionnaire of osteoporosis and osteoporosis self-assessment tool for Asia (OSTA) osteoporosis. The diagnosis of osteoporosis is based on a history of fragility fracture or results of bone mineral density determined by Dual energy X-ray absorptometry (DXA), and also need exclude secondary osteoporosis. Treatments include lifestyle adjustment, bone health supplements, and anti-osteoporosis medications. This article also compare the efficacy, safety and convenience of anti-osteoporosis drugs, and introduce new anti-osteoporosis drugs.